Harson Chlorpromazine Side effects

• Side effects of Harson Chlorpromazine in details
• Harson Chlorpromazine contraindications
• Harson Chlorpromazine reviews

What are the possible side effects of Harson Chlorpromazine?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

High doses or long-term use of Harson Chlorpromazine can cause a serious movement disorder that may not be reversible. Symptoms of this disorder include uncontrollable muscle movements of your lips, tongue, eyes, face, arms, or legs. The longer you take Harson Chlorpromazine, the more likely you are to develop a serious movement disorder. The risk of this side effect is higher in women and older adults.

Call your doctor at once if you have:

• uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement);

• stiffness in your neck, tightness in your throat, trouble breathing or swallowing;

• sudden weakness or ill feeling, fever, chills, sore throat, swollen gums, painful mouth sores, pain when swallowing, skin sores, cold or flu symptoms, cough;

• pale skin, easy bruising or bleeding;

• jaundice (yellowing of the skin or eyes); or

• severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out.

Older adults may be more likely to have side effects from this medication.

Common side effects may include:

• drowsiness;

• breast swelling or discharge;

• changes in menstrual periods;

• dry mouth or stuffy nose, blurred vision;

• constipation; or

• impotence, trouble having an orgasm.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Side effects of Harson Chlorpromazine in details

Minor Adverse Reaction: Nasal stuffiness, dry mouth, insomnia, agitation.

Liver Function: Jaundice, usually transient, occurs in a very small percentage of patients taking Harson Chlorpromazine. A premonitory sign may be sudden onset of fever after 1-3 weeks of treatment followed by the development of jaundice. Harson Chlorpromazine jaundice has the biochemical and other characteristics of obstructive jaundice and is associated with obstructions of the canaliculi by bile thrombi; the frequent resence of an accompanying eosinophilia indicates the allergic nature of this phenomenon. Treatment should be withheld on the development of jaundice.

Cardio-Respiratory: Hypotension, usually postural, commonly occurs. Elderly or volume-depleted subjects are particularly susceptible; it is more likely to occur after IM administration.

Cardiac arrhythmias, including atrial arrhythmia, AV block, ventricular tachycardia and fibrillation have been reported during neurologic therapy, possibly related to dosage. Preexisting cardiac dosage, old age, hypokalemia and concurrent tricyclic antidepressants may predispose. ECG changes, usually benign, include widened QT interval, ST depression, U-waves and T-waves changes.

Respiratory depression is possible in susceptible patients.

Blood: A mild leucopenia occurs in up to 30% of patients on prolonged high dosage. Agranulocytosis may occur rarely; it is not dose-related. The occurrence of unexplained infections or fever requires immediate hematological investigation.

Extrapyramidal: Acute dystonias or dykinesias, usually transitory are more common in children and young adults and usually occur within the first 4 days of treatment or after dosage increases.

Akathisia characteristically occurs after large initial doses.

Parkinsonism is more common in adults and the elderly. It usually develops after weeks or months of treatment. One or more of the following may be seen: Tremor, rigidity, akinesia or other features of parkinsonism. Commonly, just tremor.

Tardive Dyskinesia: If this occurs, is it usually but not necessarily, after prolonged or high dosage. It can even occur after treatment has been stopped. Dosage should be kept low whenever possible.

Skin and Eyes: Contact skin sensitization is a serious but rare complication in those frequently handling preparations of Harson Chlorpromazine. The greatest care must be taken to avoid contact of Harson Chlorpromazine with the skin. Skin rashes of various kinds may also be seen in patients treated with Harson Chlorpromazine. Patients on high dosage should be warned that they may develop photosensitivity in sunny weather and should avoid exposure to direct sunlight.

What is the most important information I should know about Harson Chlorpromazine?

• Harson Chlorpromazine syrup may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Harson Chlorpromazine syrup with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Do not drink alcohol while you are using Harson Chlorpromazine syrup.
• Check with your doctor before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Harson Chlorpromazine syrup; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
• Harson Chlorpromazine syrup may cause dizziness, light-headedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
• Do not become overheated in hot weather or while you are being active; heatstroke may occur.
• Harson Chlorpromazine syrup may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Harson Chlorpromazine syrup. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
• Harson Chlorpromazine syrup may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.
• Some patients who take Harson Chlorpromazine syrup may develop muscle movements that they cannot control. This is more likely to happen in elderly patients, especially women. The chance that this will happen or that it will become permanent is greater in those who take Harson Chlorpromazine syrup in higher doses or for a long time. Muscle problems may also occur after short-term treatment with low doses. Tell your doctor at once if you have muscle problems with your arms; legs; or your tongue, face, mouth, or jaw (eg, tongue sticking out, puffing of cheeks, mouth puckering, chewing movements) while taking Harson Chlorpromazine syrup.
• Neuroleptic malignant syndrome (NMS) is a possibly fatal syndrome that can be caused by Harson Chlorpromazine syrup. Symptoms may include fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; and sweating. Contact your doctor at once if you have any of these symptoms.
• Tell your doctor or dentist that you take Harson Chlorpromazine syrup before you receive any medical or dental care, emergency care, or surgery.
• Harson Chlorpromazine syrup may increase the amount of a certain hormone (prolactin) in your blood. Symptoms may include enlarged breasts, missed menstrual period, decreased sexual ability, or nipple discharge. Contact your doctor right away if you experience any of these symptoms.
• Harson Chlorpromazine syrup may raise or lower your blood sugar. High blood sugar may make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. Low blood sugar may make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your vision change; give you a headache, chills, or tremors; or make you hungrier. If these symptoms occur, tell your doctor right away.
• Diabetes patients - Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
• Harson Chlorpromazine syrup may cause the results of some pregnancy tests to be wrong. Check with your doctor if you have questions or concerns about your pregnancy test results.
• Harson Chlorpromazine syrup may interfere with certain lab tests, including phenylketonuria (PKU) tests. Be sure your doctor and lab personnel know you are taking Harson Chlorpromazine syrup.
• Lab tests, including liver function, complete blood cell counts, and eye exams, may be performed while you use Harson Chlorpromazine syrup. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
• Use Harson Chlorpromazine syrup with caution in the ELDERLY; they may be more sensitive to its effects, especially dizziness, light-headedness (especially upon standing), rapid heartbeat, breathing problems, urinary retention, and constipation.
• Harson Chlorpromazine syrup should not be used in CHILDREN younger than 6 months old; safety and effectiveness in these children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Harson Chlorpromazine syrup while you are pregnant. Using Harson Chlorpromazine syrup during the third trimester may result in uncontrolled muscle movements or withdrawal symptoms in the newborn. Discuss any questions or concerns with your doctor. Harson Chlorpromazine syrup is found in breast milk. Do not breast-feed while taking Harson Chlorpromazine syrup.

If you stop taking Harson Chlorpromazine syrup suddenly, you may have WITHDRAWAL symptoms. These may include nausea, vomiting, dizziness, and tremors.

Harson Chlorpromazine contraindications

Stop using this medication and call your doctor at once if you have twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs. These could be early signs of dangerous side effects.

Harson Chlorpromazine is not for use in psychotic conditions related to dementia. Harson Chlorpromazine may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

Do not use Harson Chlorpromazine if you have brain damage, bone marrow depression, or are also using large amounts of alcohol or medicines that make you sleepy. Do not use if you are allergic to Harson Chlorpromazine or other phenothiazines.

Before you take Harson Chlorpromazine, tell your doctor if you have liver or kidney disease, heart disease or high blood pressure, glaucoma, severe breathing problems, past or present breast cancer, low levels of calcium in your blood, adrenal gland tumor, enlarged prostate or urination problems, a history of seizures, Parkinson's disease, or if you have ever had a serious side effect while using Harson Chlorpromazine or similar medicines.

Before taking Harson Chlorpromazine, tell your doctor about all other medications you use.

References

1. DailyMed. "CHLORPROMAZINE: DailyMed provides trustworthy information about marketed drugs in the United States. DailyMed is the official provider of FDA label information (package inserts).". https://dailymed.nlm.nih.gov/dailyme... (accessed September 17, 2018).
2. DTP/NCI. "chlorpromazine: The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/s... (accessed September 17, 2018).
3. European Chemicals Agency - ECHA. "Chlorpromazine: The information provided here is aggregated from the "Notified classification and labelling" from ECHA's C&L Inventory. ". https://echa.europa.eu/information-o... (accessed September 17, 2018).

Reviews

The results of a survey conducted on ndrugs.com for Harson Chlorpromazine are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Harson Chlorpromazine. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.

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Information checked by Dr. Sachin Kumar, MD Pharmacology